Wednesday, October 30, 2019

Comparison of world views in the universe next door Essay

Comparison of world views in the universe next door - Essay Example The book then progresses to shoe how ensuing world views, including naturalism, deism, nihilism and existentialism, have developed from Christian Theism and where they have deviated. Sire also sheds light upon their weaknesses and where they have failed. The book further discusses how Eastern Pantheism and post modernism have affected western culture and its world views. The book is written as sort of a manual that will help Christians understand why they hold the views they do. Sire believes that knowing one’s own views is of great significance. Thus, right in the beginning, the author clearly highlights the prerequisite for being â€Å"fully conscious intellectually†, which is to be fully aware of one’s own worldview and to know exactly why one holds that view despite so many other views that surround one. From Sire’s definition we see that the ‘world view’ has a set of essential points that distinguish it. Firstly, in a world view an idea o r concept or thought is presupposed, assumed or implicitly understood. This implies that people holding a world view have laid faith or belief upon something that has led them to presuppose this idea or concept or thought. Secondly, these views are about something that people believe to be reality, that is, our world. In a sense, a world view is a belief about the reality of the world in which a person lives. Thirdly, these assumptions are held either consciously or sub-consciously but are influenced by something external to the person.

Monday, October 28, 2019

Admitted to hospital Essay Example for Free

Admitted to hospital Essay As the days passed, Mr. Glen succeeded. Now he started to teach her how to use a typewriter. She picked up his instructions very quickly. In some days she became able to write ten words in one minute. Unfortunately she failed in her exams. She cried a lot because she thought that her work was totally dark but Mr. Glen tried to give her understanding that you could try again. He told her Your work wasnt dark. It was very psychedelic. Dont lose hope. You will get success someday. Near eight O clock in the evening suddenly they made a plan to go out to eat ice cream. When they reached the ice cream shop, Mr. Glen asked Lorraine to sit on the bench and he would be back with the ice cream. She agreed and Mr. Glen went towards the ice cream shop but at once he forgot every thing even about himself: who he was and why he come there. He went back to home but unfortunately Lorraine was waiting for him. Propitiously the teacher at Lorraines university was passing that street where Lorraine was sitting. He took Lorraine with him and dropped her in her home. Lorraine opened the door of her room; Mr.  Glen was sat there. Lorraine asked her why you left me there and return home? . Mr. Glen didnt reply because he didnt know what was going on. He started to forget every thing even Lorraine because of his old age. Lorraine got frightened that if her teacher forget every thing what would happen with her future. Her parents were able to understand her sign language so she spoke to her father about her teachers health. So Mr. Callam decided that he needed doctors treatment so he got admitted to hospital. Every evening Lorraine went to the hospital to meet her teacher. She had a hope that he would be cured eventually. Chapter 4 Now Lorraine is fourty years old. She had a graduation day at her university. The principal of her university announced that Lorraine is the pride of his university. He asked her to come on the stage to get an award by him for achieving graduation. At last she fulfilled the dream of her teacher Mr. Glen. Her principal told her to express her feelings. Her parents were also present there so her mother translated her signs for other people. She said I got this level just because of my honorable teacher Mr. Glen. He worked very hard and he spends his whole life towards making my future. He taught me manners, how to spend my life. Because of him, I learnt how to eat. He taught me all the things that were impossible. He taught me dark is not black. It is the colour of achievement, colour of knowledge. She told the audience that she wanted her teacher Mr. Glen to come there and look at her with her precious award but unfortunately he couldnt come. She said, If he came here I am sure that he would be happier than me because today I have completed his dream. Then Lorraine went to the hospital to show her award to Mr. Glen. She said to him Look at this award which you have wanted for fourty years. Today I have completed your dream. Unfortunately, he didnt remember anything. Now she started trying her best to give him his memorial. She thought that Mr. Glen was the best teacher in the whole world who taught her to achieve what was impossible. Moral: Nothing is impossible if we work hard!

Saturday, October 26, 2019

Distinguishing the Difference in News Coverage among International and

Distinguishing the Difference in News Coverage among International and Domestic Images Not Included Identifying a Variance in News Coverage It became evident throughout our investigation that separating domestic news source sites from international news source sites would be beneficial in addressing our question of the variance in coverage among these news sources when identifying natural disasters throughout the world. With the objective of properly addressing this inquiry, we decided upon a proposition in order to accurately identify whether a difference in news source coverage truly exists. Therefore, we propose that world reports provide more specifications about international involvement in natural disasters rather than reports from the United States alone. This as a result insinuates that U.S. reports will have present information about U.S. aid and involvement. In turn, to properly address this proposal, we have further dissected the topic of discussion into five segments that will equally address the above mentioned proposal and discuss how the global culture manifests as it comes into being. Consequently, the di scussion of domestic rebuilding; foreign aid; poverty stricken areas; displaced families and populations; and, environmental cause and effect will be the five subtopics identifying the variance among news sources in alignment with our proposal. Before diverging into subtopics regarding natural disasters, it will be important to discuss more technical aspects of the research in order to visualize the research we were presented with. First, a total of 26 stories were tagged throughout the two month span for our group to further research. Once tagging articles was completed, it became clear that there were not ... ...h 2007 . â€Å"Queensland to Drink Waste Water.† BBC UK 29 January 2007. 29 January 2007 . â€Å"Rains Worsen Indonesia’s Flooding.† CNN World 09 February 2007. 09 February 2007 . â€Å"Rescue Efforts Intensify After Quake.† CNN 07 March 2007. 07 March 2007 . â€Å"Rescue Efforts Intensify After Quake.† CNN World 07 March 2007. 07 March 2007 . â€Å"Thousands Ill, as Jakarta Cleans up After Flood† CNN 12 February 2007. 12 February 2007 .

Thursday, October 24, 2019

Management and Information Systems

Management Information Systems: Managing the Digital Firm, 11e (Laudon/Laudon) Chapter 1 Information Systems in Global Business Today 1) Internet advertising is growing at a rate of more than 25 percent a year. Answer: TRUE 2) Developing a new product, fulfilling an order, and hiring a new employee are examples of business processes. Answer: TRUE 3) A fully digital firm produces only digital goods or services. Answer: FALSE 4) A business model describes how a company produces, delivers, and sells a product or service to create wealth. Answer: TRUE ) Information technology (IT) consists of all the hardware that a firm needs to use in order to achieve its business objectives, whereas information systems consist of all the software and business processes needed. Answer: FALSE 6) Computers are only part of an information system. Answer: TRUE 7) Information systems literacy describes the behavioral approach to information systems, whereas computer literacy describes the technical approach . Answer: FALSE 8) The dimensions of information systems are management, organizations, and information technology. Answer: TRUE 9) Knowledge workers assist with paperwork at all levels of the firm.Answer: FALSE 10) In order to understand how a specific business firm uses information systems, you need to know something about the hierarchy and culture of the company. Answer: TRUE 11) Business processes are logically related tasks for accomplishing tasks that have been formally encoded by an organization. Answer: FALSE 12) There are four major business functions: Sales and marketing; manufacturing and production; finance and accounting; and information technology. Answer: FALSE 13) A network requires at least two computers and a shared resource, such as a printer.Answer: FALSE 14) A substantial part of management responsibility is creative work driven by new knowledge and information. Answer: TRUE 15) Intranets allow firms to work easily with third-party suppliers and vendors. Answer: FALSE 16) An IT infrastructure provides the platform on which the firm can build its information systems. Answer: TRUE 17) UPS's use of Web-based tools that allow customers to embed UPS functions such as tracking and cost calculations into their own Web sites was an information systems solution used to achieve customer intimacy.Answer: TRUE 18) Government and private sector standards are examples of complementary social assets required to optimize returns from IT investments. Answer: TRUE 19) A firm that invests in efficient business processes is making an investment in organizational complementary assets. Answer: TRUE 20) In the behavioral approach to information systems, technology is ignored in favor of understanding the psychological, social, and economic impacts of systems. Answer: FALSE 1) The six important business objectives of information technology are new products, services, and business models; customer and supplier intimacy; survival; competitive advantage; operational excellence; and A) improved flexibility. B) improved decision making. C) improved business practices. D) improved efficiency. Answer: B 22) Dell Computer's use of information systems to improve efficiency and implement â€Å"mass customization† techniques to maintain consistent profitability and an industry lead illustrates which business objective? A) improved flexibility B) improved business practices C) competitive advantageD) survival Answer: C 23) The use of information systems because of necessity describes the business objective of A) survival. B) improved business practices. C) competitive advantage. D) improved flexibility. Answer: A 24) Which of the following choices may lead to competitive advantage: (1) new products, services, and business models; (2) charging less for superior products; (3) responding to customers in real time? A) 1 only B) 1 and 2 C) 2 and 3 D) 1, 2, and 3 Answer: D 25) Verizon's implementation of a Web-based digital dashboard to provide manage rs with real-time information such as customer complaints is an xample of A) improved flexibility. B) improved decision making. C) improved efficiency. D) customer and supplier intimacy. Answer: B 26) The move of retail banking to use ATMs after Citibank unveiled its first ATMs illustrates the use of information systems to achieve which business objective? A) improved efficiency B) customer and supplier intimacy C) survival D) competitive advantage Answer: C 27) An information system can be defined technically as a set of interrelated components that collect, process, store, and distribute information to support A) decision making and control in an organization.B) communications and data flow. C) managers analyzing the organization's raw data. D) the creation of new products and services. Answer: A 28) The three activities in an information system that produce the information organizations use to control operations are A) information retrieval, research, and analysis. B) input, outp ut, and feedback. C) input, processing, and output. D) data analysis, processing, and feedback. Answer: C 29) Order data for baseball tickets and bar code data are examples of A) raw input. B) raw output. C) customer and product data. D) sales information. Answer: A 0) The average number of tickets sold daily online is an example of A) input. B) raw data. C) meaningful information. D) feedback. Answer: C 31) Output A) is feedback that has been processed to create meaningful information. B) is information that is returned to appropriate members of the organization to help them evaluate the input stage. C) transfers data to the people who will use it or to the activities for which it will be used. D) transfers processed information to the people who will use it or to the activities for which it will be used. Answer: D 32) Converting raw data into a more meaningful form is called A) capturing.B) processing. C) organizing. D) feedback. Answer: B 33) An example of raw data from a nationa l chain of automobile stores would be A) an average of 13 Toyotas are sold daily in Kentucky. B) 30 percent increase in Toyota RAV 4 sales during September in Kentucky. C) 1 Toyota RAV4 sold March 3, 2008 in Louisville, Kentucky. D) all of the above. Answer: C 34) The field that deals with behavioral issues as well as technical issues surrounding the development, use, and impact of information systems used by managers and employees in the firm is called A) information systems literacy.B) information systems architecture. C) management information systems. D) information technology infrastructure. Answer: C 35) In a hierarchical organization, the upper levels consist of A) managerial and professional employees. B) managerial, professional, and technical employees. C) professional and operational employees. D) managerial, professional, and operational employees. Answer: B 36) Which of the six strategic business objectives did the NBA's use of Synergy Sports Technology help to achieve? A) customer and supplier intimacy B) improved decision makingC) new products and services D) operational excellence Answer: B 37) The fundamental set of assumptions, values, and ways of doing things that has been accepted by most of a company's members is called its A) culture. B) environment. C) atmosphere. D) values. Answer: A 38) Thomas Friedman's declaration that the world was now â€Å"flat† meant that A) the Internet has reduced the economic advantages of developed countries. B) globalization is starting to offer less advantage to large corporations. C) the global economy is increasingly commanded by fewer and larger corporations.D) global capitalism is homogenizing culture and business practices throughout the world. Answer: A 39) Data management technology consists of the A) physical hardware and media used by an organization for storing data. B) detailed, preprogrammed instructions that control and coordinate the computer hardware components in an information system . C) software governing the organization of data on physical storage media. D) hardware and software used to transfer data. Answer: C 40) The hardware and software used to transfer data in an organization is called A) data management technology.B) networking and data management technology. C) data and telecommunications technology. D) networking and telecommunications technology. Answer: D 41) Networking and telecommunications technologies, along with computer hardware, software, data management technology, and the people required to run and manage them, constitute an organization's A) data management environment. B) networked environment. C) IT infrastructure. D) information system. Answer: C 42) An example of a business using information systems to create new products and services is A) Wal-Mart's RetailLink system.B) the Mandarin Oriental hotel's customer-preference tracking system. C) Verizon's Web-based digital dashboard. D) Apple Inc. ‘s iPod. Answer: D 43) An example of a business using information systems to attain operational excellence is A) Wal-Mart's RetailLink system. B) the Mandarin Oriental hotel's customer-preference tracking system. C) Verizon's Web-based digital dashboard. D) Apple Inc. ‘s iPod. Answer: A 44) An example of a business using information systems for customer and supplier intimacy is A) Wal-Mart's RetailLink system. B) the Mandarin Oriental hotel's customer-preference tracking system.C) Verizon's Web-based digital dashboard. D) Apple Inc. ‘s iPod. Answer: B 45) Maintaining the organization's financial records is a central purpose of which main business function? A) manufacturing and accounting B) finance and accounting C) sales and manufacturing D) finance and sales Answer: B 46) Based on the examples in the chapter, if you were asked to formulate a plan for a regional drive-in restaurant chain's efforts to use information technology to develop a loyal customer base, what would be the best use of information tec hnology from the list below? A) Use IT to increase supplier loyalty.B) Use IT to increase operational efficiency. C) Use IT to create new products and business models. D) Use IT to help survive government reporting requirements. E) Use IT to achieve customer intimacy. Answer: E 47) The fact that online advertising revenues are growing at 25 percent a year, while offline traditional advertising revenues are growing at about 5 percent a year, suggests that A) Internet advertising is very inexpensive. B) offline traditional advertising is not very effective. C) the Internet is transforming the traditional advertising business model.D) new technologies are more efficient at selling to customers. Answer: C 48) Toyota Motor Company's vehicle orders management system allows it to improve efficiency by basing vehicle production on A) superior forecasts of regional demand. B) actual customer orders. C) improved decision making. D) customer preferences. Answer: B Diff: 3Page Ref: 15 AACSB: Us e of information technology CASE: Content Objective: 1. 1 49) In a business hierarchy, the level that is responsible for monitoring the daily activities of the business is A) middle management.B) service workers. C) production management. D) operational management. Answer: D 50) Which of the following are environmental actors that interact with an organization and its information systems? A) customers B) suppliers C) regulatory agencies D) all of the above Answer: D 51) From a business perspective, raw data is transformed systematically during various stages, transforming it into valuable information, in a process called A) the information value chain. B) the IT value chain. C) information processing. D) feedback. Answer: A 2) A corporation that funds a political action committee, which in turn promotes and funds a political candidate who agrees with the values of that corporation, could be seen as investing in which main category of complementary assets? A) managerial B) government al C) social D) organizational Answer: C 53) Apple Computer dominates the online legal music sales industry primarily because of a failure of recording label companies to A) invest in technology. B) adopt a new business model. C) invest in complementary assets. D) modernize their information value chain. Answer: B 54) An example of an organizational complementary asset isA) using the appropriate business model. B) a collaborative work environment. C) laws and regulations. D) all of the above. Answer: A 55) An example of a social complementary asset is A) technology and service firms in adjacent markets. B) training programs. C) distributed decision-making rights. D) all of the above. Answer: A 56) Disciplines that contribute to the technical approach to information systems are: A) computer science, engineering, and networking. B) operations research, management science, and computer science. C) engineering, utilization management, and computer science.D) management science, computer science, and engineering. Answer: B 57) The discipline that focuses on mathematical techniques for optimizing parameters of organizations, such as transportation and inventory control, is A) management science. B) MIS. C) operations research. D) utilization management. Answer: C 58) Sociologists study information systems with an eye to understanding A) how systems affect individuals, groups, and organizations. B) how human decision makers perceive and use formal information. C) how new information systems change the control and cost structures within the firm.D) the production of digital goods. Answer: A 59) Psychologists study information systems with an eye to understanding A) how systems affect individuals, groups, and organizations. B) how human decision makers perceive and use formal information. C) how new information systems change the control and cost structures within the firm. D) the production of digital goods. Answer: B 60) The costs for firms operating on a global scal e have been drastically reduced by A) networking technology. B) investments in organizational complementary assets. C) the Internet. D) the rise of digital content. Answer: C 1) Which of the following are key corporate assets? A) intellectual property, core competencies, and financial and human assets B) production technologies and business processes for sales, marketing, and finance C) knowledge and the firm's tangible assets, such as goods or services D) time and knowledge Answer: A 62) Overproduction or underproduction of goods and services, misallocation of resources, and poor response times are the results of a firm's having A) poor relationships with suppliers. B) poor relationships with customers. C) inadequate information. D) a surplus of information.Answer: C 63) A firm that must invest in new information systems capabilities in order to comply with federal legislation can be said to be investing to achieve which business objective? A) customer intimacy B) operational excel lence C) survival D) improved reporting Answer: C 64) Which of the following would NOT be used as an input for an information system? A) digital dashboard B) handheld computer C) bar-code scanner D) cell phone Answer: A 65) Which field of study focuses on both a behavioral and technical understanding of information systems? A) sociology B) operations research C) economicsD) management information systems Answer: D 66) The three principle levels within a business organization hierarchy are A) senior management, operational management, and service workers. B) senior management, middle management, and operational management. C) senior management, operational management, and information systems. D) senior management, middle management, and service workers. Answer: B 67) Engineers, scientists, or architects, who design new products or services for a firm, belong to which level of a business hierarchy? A) middle management B) production workers C) knowledge workersD) data workers Answer: C 68) Which main business function is responsible for maintaining employee records? A) sales and marketing B) human resources C) finance and accounting D) manufacturing and production Answer: B 69) Which of the following constitutes an organizational element in the UPS tracking system described in the chapter? A) the specification of procedures for identifying packages with sender and recipient information B) monitoring service levels C) promoting the company strategy of low-cost, superior service D) the use of handheld computers and networks for managing package delivery Answer: A 0) A managerial element in the UPS tracking system described in the chapter is A) taking inventory. B) providing package status reports to customers. C) the decision to use automation. D) in-house package tracking software. Answer: C 71) ________ is data that has been shaped into a form that is meaningful to human beings. Answer: Information 72) ________ is output returned to appropriate members of the or ganization to help them evaluate or correct the input stage. Answer: Feedback 73) ________ is a global network that uses universal standards to connect millions of different networks around the world.Answer: The Internet 74) Computer ________ consists of the detailed, preprogrammed instructions that control and coordinate the computer hardware components in an information system. Answer: software 75) The ________ is a service provided by the Internet that uses universally accepted standards for storing, retrieving, formatting, and displaying information in a page format. Answer: World Wide Web/Web/WWW 76) ________ are private corporate networks extended to authorized users outside the organization. Answer: Extranets 7) The key elements of an organization are its people, structure, business processes, politics, and ________. Answer: culture 78) In a(n) ________ perspective, the performance of a system is optimized when both the technology and the organization mutually adjust to one a nother until a satisfactory fit is obtained. Answer: sociotechnical 79) ________ makes long-range strategic decisions about the firm's products and services. Answer: Senior management 80) Investments in organization and management, such as investments in new business models and training, are also known as ________.Answer: organizational and management capital 81) Define operational excellence. How can information systems help achieve it? Answer: Operational excellence is the achievement of higher levels of productivity, efficiency, profitability. Information systems can help achieve operational excellence by improving communications to supplier and optimizing the supply chain. Information systems could help managers communicate with workers more efficiently, enable technological innovation in products, minimize warehouse overhead, streamline distribution. 82) You work for an auto manufacturer and distributor.How could you use information systems to achieve greater customer intimacy? Answer: You could create a Web site that allows customers to customize cars, communicate with support personnel and other car owners. You could create an automated e-mail service reminding car owners to take their car in for periodic checkups. You could have an information system that tracks customer preferences in local areas, so you can provide cars that reflect local customer needs and desires. 83) What is the difference between information technology and information systems? Describe some of the functions of information systems.Answer: Information technology (IT) consists of all the hardware and software that a firm needs to use to achieve its business objectives. Information systems are more complex. An information system can be defined technically as a set of interrelated components that collect (or retrieve), process, store, and distribute information to support decision making and control in an organization. An information system: †¢supports decision making, coordinati on, and control †¢helps employees analyze problems †¢helps employees visualize complex subjects †¢helps create new products 4) You are a marketing manager for a national movie theater chain. Give an example of data that your department could use for creating meaningful information. What type of information could that data produce? Answer: Movie ticket sales from individual theaters would be an example of raw data. Meaningful information from this would be: average number of tickets sold to seniors on certain days of the week. 85) Define business process. What might be a business process used at a hospital? Answer: A business process is a set of logically related tasks and behaviors for accomplishing work.Hiring a new employee, customer intake, and filing medical records are examples of business processes at a hospital. 86) You are starting a small bike messenger company. Given your type of services (hand-delivering packages within a small geographical area), could you r firm be a digital firm? If so, what would make this a digital firm? Answer: Being a digital firm doesn't purely rely on having digital goods and services. A digital firm would have most of its relationships with customers, suppliers, and employees be digitally enabled.Ordering deliveries, assigning deliveries, managing employees and assignments could certainly be digitally enabled; using cell phones, information systems, and handheld devices to connect customers, delivery management, and bike messengers. 87) This chapter discusses how each organization has its own culture and sets of values shared by most of its members. What kind of shared values might you find at a law firm? Answer: Shared values at a law firm might be: The legal system works, the legal system is fair, lawyers help people, and people need help with the legal system because it is complicated. 8) You work at the business headquarters for a chain of movie theaters. Describe this firm's information value chain. Answ er: An information value chain adds value to data at various stages, transforming it into valuable data. At a chain of movie theaters, data would be gathered from ticket sales and concession sales. Information systems would help transform this into meaningful information, such as determining the types of movies popular in certain regions, times and days of the week that people most often saw movies, what snacks were the most popular.This information would be valuable in making decisions, such as offering ticket discounts during less popular time slots, and offering more popular snack items. Further feedback based on the results of these decisions could determine whether these decisions were effective. 89) How does a company's use of information systems affect its corporate strategies? Provide an example. Answer: A firm's ability to effectively use information technology is interdependent with its ability to implement corporate strategies and achieve corporate goals.More and more, th e ability to compete and succeed depends on a company's ability to implement technology. What a business would like to do in the future can depends on what its systems will be able to do. Examples of this might be a company who invests in information systems that enable it to create new products or to make its distribution system more efficient, allowing the company to become the low-cost producer. 90) The information systems of Accenture, a global consulting firm, allow for a highly decentralized organization without a traditional headquarters.Based on your reading of Chapter 1, which of the six strategic business objectives does Accenture's information systems contribute to? Answer: Student answers will vary. The following is an example of a possible answer: Accenture's information systems allow its mobile workforce to be within easy, constant reach of its customers, contributing to the business objective of customer and supplier intimacy. Additionally, the ability of employees to connect to and work with local branch information systems in standard ways, regardless of their location, contributes to more efficient processes and operational excellence.

Wednesday, October 23, 2019

Esterification

To synthesis ecstatically acid by stratification. Introduction: A pleasant, often fruity, odor is characteristic of some of the simpler esters. Ethyl butyrate smells similar to pineapples, the odor of n-propel acetate is reminiscent of pears and isopleths acetate has a strong banana fragrance. Esters are derivatives of the carboxylic acids and contain the following functional group: The synthesis of an ester can be accomplished in one of several ways. An stratification occurs when an alcohol and a carboxylic acid are reacted in the reserve of a mineral acid catalyst, such as sulfuric acid.Because these reactions result in an equilibrium mixture of both products and reactants, the reaction conditions must be manipulated in order to produce a reasonable yield. A large excess of one of the reactants can be used in the starting mixture or alternatively, one of the products can be removed as the reaction proceeds (as by a distillation), to shift the equilibrium to the right. Other synthet ic pathways to esters also exist. Acid chlorides react with alcohols to yield an ester and hydrochloric acid.A small amount of pyridine is usually deed to the reaction mixture to neutralize the resulting acid. Acid anhydride can also react with alcohols to produce esters. Unlike the reactions between carboxylic acids and alcohols, neither of these two methods for preparing esters results in an equilibrium mixture. Ecstatically acid, or aspirin, is one of the most widely used and versatile drugs known today. It was first synthesized by Charles von Gerhardt in 1 853 and was later patented by a German dye chemist named Frederica Brayer in 1893 who recognized its potential as an analgesic (pain reliever).Salicylic acid, a impotent of willow and poplar bark, had been used as a pain killer for centuries, but its highly acidic property caused irritation of the mucous membranes of the mouth and throat and also resulted in uncomfortable gastric pain. By transforming the acidic phenol functio nality into an ester group, the compound retained its analgesic properties but lost some of its irritating side- effects. In addition to relieving pain, aspirin is also an antipathetic (fever reducer) and an anti-inflammatory agent (used for arthritis). Like all drugs, aspirin also has some undesirable side effects which should be tote.When taken in large quantities (several grams per day), gastric problems can result. Its use has been implicated in Rexes syndrome, a brain disorder that can affect people under the age of 18. Some people are highly allergic to aspirin. Finally, aspirin interferes with platelets and affects normal blood clotting which can lead to hemorrhaging in extreme cases. However, its anticoagulant properties can also be used to advantage in preventing blood clots from forming in the arteries. Recent studies have shown that the consumption of one half of an aspirin tablet per day can help to prevent heart attacks and strokes.Aspirin can be synthesized by the stra tification of salicylic acid via reaction with acetic anhydride. A few drops of phosphoric acid are added to serve as a catalyst for the reaction. The use of acetic anhydride as a reactant, instead of acetic acid, results in a rapid and irreversible conversion of salicylic acid to ecstatically acid. Experimental Procedure: Synthesis of ecstatically acid 1 . A 400 ml beaker containing about 150 ml of water was heated to the boiling point on a hot plate. 2. 2 g of salicylic acid was weighed out and it was placed in a 100 ml conical flask. . 5 ml of acetic anhydride was added into the conical flask. . 5 drops of 85% phosphoric acid, HAPPY was added. The flask was swirled to mix the reactants and then it was clamped in the boiling water bath. It was heated for about 8 minutes. 5. The flask was removed carefully from the hot water bath and the hot plate was turned off. 2 ml of distilled water was added cautiously to the flask. The water will react with any unrelated acetic anhydride whic h remains. 6. Once the reaction between acetic anhydride and water had subsided, 40 ml Of water Was added to the flask. 7. The contents was allowed to cool at room temperature for minutes then the flask was placed in ice. . The contents was stirred with a glass rod periodically during this cooling period. The solid product was collected by vacuum filtration and it was washed with cooled water. 9. A small portion (spatula-tip full, 20-30 MGM) of this crude ecstatically acid was set aside. 10. To recitalist the ecstatically acid, it was transferred to a 100 ml conical flask and 10 ml of 95% ethanol was added. 1 1. The flask was heated slowly on a hot plate just until the aspirin completely dissolved. As soon as all of the solid has dissolved, the flask was removed from the hot plate. 12.Water was added to the solution in 5 ml portions, it was swirled after each addition, until a total of 40 ml of water has been added. 13. The flask was placed in an ice bath for 10 minutes to complete the crystallization. 14. The purified aspirin was collected by vacuum filtration. The crystals was washed in the funnel with ice-cold water. The vacuum was left on for a few minutes to air dry the purified aspirin, the crystals was then pressed between two pieces of filter paper to thoroughly dry them. 5. The mass, yield and melting point of dried aspirin were obtained. Results: Weight of salicylic acid used: 2. 0021 g Weight of watch glass: 20. 536 g Weight of watch glass t product: 21. 6651 g Weight of product: 1. 3115 g no. Of mole of salicylic acid: = 0. 01450 mol Volume Of acetic anhydride used 5 ml Density of acetic anhydride = 1. 082 g/ml Mass of acetic anhydride used = 1. 082 g/ml x 5 ml = 5. 41 g no. Of mole of acetic anhydride: – 0. 0530 mol = 3. 66>1 Since the mol of salicylic acid is smaller than the mol of acetic anhydride, salicylic acid is a limiting agent. Mol of salicylic acid produced 1 mol of ecstatically acid. 0. 01450 mol of salicylic acid produced 0. 014 50 mol of ecstatically acid. Theoretical weight of ecstatically acid: 0. 1450 mol x 180. 16 gnu-mol = 2. 6123 g Percentage yield: x 100% = 50. 20 % 50 % Melting point of aspirin: 138 – 140 co Discussion: Aspirin is an effective analgesic (pain reliever), antipathetic (fever reducer) and anti-inflammatory' agent and is one of the most widely used non-prescription drugs. The active ingredient in aspirin was found to be salicylic acid. The structure of salicylic acid is shown below. In this experiment, aspirin is formed from the reaction between salicylic acid and acetic anhydride through stratification. Aspirin can be made by reacting salicylic acid with acetic acid in the presence of an acid catalyst.The phenol group on the salicylic acid forms an ester with the carboxylic group on the acetic acid. However, this reaction is slow and has a relatively low yield. If acetic anhydride was used instead of acetic acid, the reaction will be much faster and has a higher yield (since ac etic anhydride is much more reactive than acetic acid). Therefore, we used acetic anhydride for shorten the period f stratification. In order for reaction to occur faster, phosphoric acid was added as a catalyst. Then the solution was being placed in the hot water bath to heat up and thus triggering the reaction between salicylic acid and acetic anhydride.The reaction was shown as below: In this experiment, the salicylic acid is the limiting reactant and the acetic anhydride is in excess. The addition of distilled water into the mixture after it is being removed from the water bath is to let the water react with the remaining acetic anhydride in the mixture which are still not being reacted. A vigorous reaction will occur as the decomposition of the excess acetic anhydride is exothermic. Once the decomposition of the excess acetic anhydride has completed, more water was added, forming completing the reaction.Now the solution contains two kinds of products, which are ecstatically aci d and acetic acid, according to the reaction shown below. The reason why acetic acid is dissolved in this process but not ecstatically acid was due to the hydrogen bonding of acetic acid can form with water while ecstatically acid cannot. This is due to the large carbon group maintained by ecstatically acid which caused it to have difficulties from forming hydrogen bond with water. The aspirin collected will then be purified by rationalizations. In this purification method, the crude aspirin will be dissolved in a small amount of warm ethanol.Water was then be added and the solution was cooled slowly in the ice bath and then chilled. The ecstatically acid will recitalist, and the solid impurities (unrelated salicylic acid) should remain dissolved in the solution. The solid aspirin will again be collected using vacuum filtration. Rationalizations was needed to obtain a pure product from the crude product. Therefore, this aspirin should be more pure than the original aspirin. The fina l product was left in air dry and weighed. The theoretical and percentage yield was calculated. The weight of ecstatically acid obtained was 1. 115 g while the percentage yield of product was 50%. Besides, the melting point of ecstatically acid we obtained was in the range of 1 38 – 140 By comparing these observed melting points with the literature value of 138 – CHIC for ecstatically acid, it was found that the values were exactly the same, indicating that both rodents were ecstatically acid( previously stated as ecstatically acid and acetic acid). The above reaction was an example of an organic synthesis called stratification. Stratification is the acid catcalled reaction of a carboxylic (-COHO) group and an -OH group of an alcohol or phenol to form a carboxylic ester.In the synthesis of aspirin, the -OH group is the phenol OH group attached to ring of the salicylic acid. The acetic group, ;COACH comes from acetic anhydride, and the reaction is catcalled by phosphori c acid, HAPPY. Salicylic acid has a higher priority as it has a benzene ring which s more stable than the open chain of acetic anhydride because it has more resonance. Salicylic acid reacts better with acetic anhydride than acetic acid, so acetic acid will provide the acetic group which will react with the alcoholic – OH group on the salicylic acid.The hydrogen ion from the hydroxyl group in the salicylic acid breaks away first, then combines with the oxygen which has a negative charge after acetic anhydride is broken into two parts, which are an alkyl carbonyl group and -?CHOC- group. This is how acetic acid is formed. Later on, the alkyl carbonyl group of acetic anhydride which now has positive charge due to the lack Of oxygen atom, connects to the oxygen atom which has a negative charge, lastly produced ecstatically acid as a neutral compound product.The mechanism of how an ecstatically acid formed from stratification reaction will be shown: Precaution steps: 1 . When hand ling phosphoric acid, students should be aware of spill it out because it is corrosive. 2. When adding water to the heated solution, students should be careful and added in small amount of water because it may splatter to the surroundings due to the vigorous reaction. 3. The elution was allowed to cool at room temperature before putting it into the ice bath for the process of crystallization in order to get crystals in a nicer form and in correct manner.

Tuesday, October 22, 2019

Alternative Methods to Obtain Stem Cells †Science Research

Alternative Methods to Obtain Stem Cells – Science Research Free Online Research Papers In 2005, the President’s Council on Bioethics convened to discuss alternative means of deriving pluripotent stem cells. Due to the nature of a blastocyst’s cellular organization, the original procedure to cultivate pluripotent stem cells lines involved the desegregation of blastomeres in developing embryos that necessitated their untimely death1. This process at its inception brought into question the ethics of using pluripotent stem cells derived from embryos, as it meant taking life to save life. This controversy was brought to the attention of the general public and resulted in, then, President George W. Bush delivering a speech on August 9, 2001 announcing his policy decision to â€Å"allow [scientists] to explore the promise and potential of stem cell research without crossing a fundamental moral line, by providing taxpayer funding that would sanction or encourage further destruction of human embryos that have at least the potential for life.† In effect, he would allow scientific research to continue to be performed on stem cells lines that had been derived previous to that date, but would not support federally funding new stem cell lines2. Stem cell research made several minor advancements in spite of this policy, but the governmental limitations frustrated many scientists who looked to stem cells as a vast new area to be explored. Thus, the council’s main objective was to find a morally preferable way to derive healthy pluripotent cells3. Many alternatives were discussed at length, but one, I believe, has the most potential for future application. This alternative process of deriving pluripotent stem cells is the Landry-Zucker Proposal. Donald Landry and Howard Zucker of Columbia University, in their landmark review of the situation, advocated for the derivation of pluripotent stem cell lines using blastomeres surgically removed from organismically dead embryos. Drawing upon court rulings and legislative acts, they surmised that an embryo could be technically classified as dead once the cells lost the ability of â€Å"continued and integrated cellular division, growth, and differentiation.1† The idea is that even though the embryo has lost the opportunity for further development, some healthy individual cells remain and can potentially be harvested for cultivation. In some ways, this proposal is analogous to the removal of organs from a deceased human adult3. Modern day IVF clinics contain a vast resource of healthy pluripotent stem cells that are currently left unutilized. Dr. Laverge at the Department of Obstetrics and Gynaecology at the University Hospital in Belgium found a significant percentage of embryos preserved by cryogenic storage in IVF clinics do not continue cellular cleavage after being thawed; or lack the capacity for continued growth and development. There is a host of articles relating to scientists concerns that the reason behind the cessation of cleavage is solely chromosomal abnormalities1 3. This raises a serious issue of practicality as only healthy, diploid blastomeres can be used to derive normal functioning pluripotent stem cells. Addressing this issue, Dr. Laverge’s study found that approximately 11 percent of the non-cleaving embryos do not contain chromosomal abnormalities and would be suitable for pluripotent stem cell removal4. In a separate experiment by Dr. Alikani of the Institute for Reproductive Medicine and Science of Saint Barnabas, 107 non-viable embryos were used to extract 247 individual cells. 33% of these cells were found to differentiate and continue normal cellular activity when placed in a living host embryo5. This constitutes a major supply of healthy stem cells without the ethical issues surrounding the extraction procedure. The Landry-Zucker proposition circumvents the ethical issues of harming human embryos during the extraction process (as they are already dead) but new ethical issues surface due to critics concerns that IVF clinics would intentionally harm embryos to increase the number available for stem cell extraction. The two Columbia professors addressed this concern by stipulating that only embryos originally created with reproductive intent, that were thought healthy enough to be kept alive in cryogenic storage, and that, after thawing, turned out to be dead could be used to derive cell cultures1. Regulatory boards could be created to ensure these guidelines were being met, and thus, no intentionally destroyed embryos would be used for research purposes. Another practical concern resulting from this proposition is the determination of embryo death. A study analyzing the success rates of cryostorage on embryos found that 90% of recently thawed embryos that displayed no cleavage after 24 hours did not cleave any further4. This allows for an approximation system, but more exact (and less time consuming) methods are needed. The Landry-Zucker proposal suggests further studies in biochemical markers that initiate spontaneous embryo death1. If these markers were to be found, there would be a reliable way for determining embryonic death and therefore less controversy in its designation. The reason the Landry-Zucker proposal has not been widely implemented could be a result of the significant investment of initial capital (both human resources and instrumentation) required to make the leap from current IVF policies to the ones proposed. Private companies have to weigh the pros and cons of using blastomeres derived from organismically dead embryos rather than the stem-cell lines derived before the designated deadline of August 9, 2001. Stem cells obtained from the spontaneously dead embryos must first be surgically removed, cultured, and then karyotyped to determine whether the new cell colony originated from a blastomere with genetic abnormalities (such as aneuploidy). This process obviously requires time and money that would not be needed if they were taken from the original stem cells. However, as former President Bush stated, his policy was set forth to avoid the further destruction of human embryos that have the potential for life3. As the embryos in the Landry- Zucker Proposal are from spontaneously dead embryos, the procedure cannot be said to harm them. This creates a loophole in which government funding may be acquired, offsetting the initial costs while remaining a viable way to acquire diploid blastomeres without the disruption to embryonic life. A number of potential uses for human embryonic stem cells have been championed ever since a method for preparing them was discovered in 19986. Even if pluripotent stem cells relieve none of the numerous diseases scientists claim, research on these unspecialized cells will provide an invaluable understanding of the processes of cellular differentiation. Scientists must be given use of these cells to further our understanding of ourselves and our humble embryonic origins. This knowledge, however, should be acquired through procedures that respect the sanctity of life. I believe the Landry-Zucker Proposal is an ethically sound way to cultivate future pluripotent stem cell lines. References: 1. Landry, D.W., Zucker, H.A. (2004). Embryonic death and the creation of human embryonic stem cells. Journal of Clinical Investigation. 114(9), 1184-1186. (Google Scholar: Landry-Zucker Proposal, Alternative stem cells) 2. Wertz, D.C. (2002). Embryo and stem cell research in the United States: history and politics. Gene Therapy, 9, 674?678. (Google Scholar: History of stem cells in United States, George W. Speech on stem cells) 3. The Presidents Council on Bioethics. (2005). White paper: alternative sources of pluripotent stem cells. Washington, DC: U.S. Government Printing Office. (Google Scholar: Alternative sources of stem cells) 4. Laverge, H, et al. (1998). Fluorescent in-situ hybridization on human embryos showing cleavage arrest after freezing and thawing. Human Reproduction, 13, 425-429. (Google Scholar: Freezing and thawing, cryostorage, IVF clinics, human embryos) 5. Alikani, M, Willadsen, S. (2002). Human blastocysts from aggregated mononucleated cells of two or more non-viable zygote-derived embryos. Reprod. Biomed. Online, 5, 56-58. (Google Scholar: human embryos, non-viable, mortality rate, IVF clinics) 6. Thomson, JA, et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science, 282, 1145-1147. (Google Scholar: Original method for viable human stem cells, blastomeres) Research Papers on Alternative Methods to Obtain Stem Cells - Science ResearchGenetic EngineeringInfluences of Socio-Economic Status of Married MalesAnalysis of Ebay Expanding into AsiaMoral and Ethical Issues in Hiring New EmployeesEffects of Television Violence on ChildrenResearch Process Part OneBionic Assembly System: A New Concept of SelfRelationship between Media Coverage and Social andPETSTEL analysis of IndiaOpen Architechture a white paper

Monday, October 21, 2019

The Freedom Writers Diary Essays

The Freedom Writers Diary Essays The Freedom Writers Diary Essay The Freedom Writers Diary Essay The Freedom Writers Essay- Chloe Taylor How are different cultures represented in Freedom Writers? What values and attitudes do we draw from the film and its background? Cultures are shown and exposed to us in various ways everyday. Different cultures are represented in different ways in the Western Society. In the movie Freedom Writers, we witness this cultural conflict on a first hand basis. Urban youths in Freedom Writers heavily rely on respect to judge others. They also judge based on each other’s cultural back ground. Later in the film, these same teenagers begin to value education and the sense of belonging in school, rather than belonging in gangs. Gangs and groups are a part of the Western Society that we have had to learn to accept in our lives. In the feature film Freedom Writers, we are shown gangs divided up into cultures and cultural backgrounds. This has built up a lot of tension between cultures and attitudes towards other gangs. The scene in which all the students enter room 203 and take seats into their separate corners of the room divided into their certain corners of the room shows the division between students in a real life. We see a long shot of the whole classroom showing its layout and the segregation between gangs. Then multiple mid-shots are shown of the gang itself and its individual members to decipher the multiple gangs, their attitudes towards school and their way of life. Even though the students start their school year with an attitude of ignorance towards other cultures they begin to learn the value of each individual and change their point of view and their gangs and cooperate with their cultures. People may argue that respect is something that has to be earned, it is not automatic. In the 1992 Los Angeles’s race riots, respect was something that was taken for granted, as it was essential for their society. In Freedom Writers, Ms Gruwell demanded respect immediately. Not surprisingly the students refused to give it to her and why should they of, they didn’t know anything about Ms Gruwell. Towards the end of the film we see that Ms Gruwell has gradually gained the respect she wanted from her class. We are shown this in a first hand basis as Andre, a gang member, calls Ms Gruwell ‘Mam’. She takes this as an offence and claims she is not anyone’s mother; Eva soon corrects her and states that it was a ‘sign of respect to you’. This scene is shown to us by a series of close up shots of Andre, Ms Gruwell and Eva. This is purposely done to capture the changing emotion in the characters face. The students of room 203 value Ms Gruwell not only as a teacher and a person and this is reflected in their attitude and behaviour. We all know what racism is and have most likely been subjected to it or witnessed it at one time in our lives. Racism is more prominent in schools and work places although random attacks of racist acts can also be seen in the streets or at public places where the offender and the victim may not even know each other. In the feature film Freedom Writers, every student at Long Beach either dishes out racist comments or receives them. When all of the ‘unteachable’ students get integrated into the same class we see this clash of cultures collide. A racist caricature is drawn of one of the African-American students and the rest of the students find it amusing. Ms Gruwell takes the picture and compares it to the Jews during the holocaust. Erin was greeted with dumb-founded looks only to find out the kids didn’t know what the holocaust was yet they acted out their lives in a similar racist manner. This scene is shown by using close ups of Ms Gruwell and the victim of the caricature, Jamal. We see Ms Gruwell looking horrified and Jamal’s expression looking embarrassed. We are also shown mid-shots of the whole class to show their expressions and they seem amused and proud of themselves. Towards the end of the movie the students do not lash out any forms of racism at one another and instead treat each other as good friends. At the end of Freedom Writers, the students have accepted and value each other as individual people not of their cultural back ground. Ms Gruwell gained the respect she earned from devoting her life to teach these children. During this essay I have explored the movie Freedom Writers and how factors like gangs, respect and racism can have such an impact on peoples lives. It can change peoples values on life and their attitudes and behaviours towards things and that is what we draw from the film.